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However, AI can present a difficult diagnostic challenge, especially when adrenal insufficiency is partial. This is a particularly important issue as acute crises may occur during stress periods in undiagnosed patients.


Chronic transfusions induce iron overload in several organs, including adrenal and pituitary glands. In two studies, patients with TM had higher baseline adrenocorticotrophic hormone ACTH levels than do controls, suggesting primary impairment of adrenocortical function. If it is higher than normal, the patient has primary AI, whereas if it is low, the diagnosis of secondary or tertiary AI should be considered.

The second method assesses the serum cortisol values in response to exogenous corticotropin ACTH stimulation or insulin tolerance test ITT.

The text is useful for the diagnosis of AI but not for the differential diagnosis between peripheral and central forms. Unfortunately, this diagnostic approach has not been validated in patients with TM. After collecting and analysing the data, the ICET-A group prepared relevant clinical and practical recommendations for the assessment of HPA axis in these patients.

A total of 35 specialists participated in the second step questionnaire. The recommendations were based on published, peer-reviewed scientific evidence, expert opinion, and accumulated professional knowledge and experience.

Recommendations from published guidelines were used when available and appropriate. The ICET-A Network also issued expert consensus opinions on topics for which limited or low level evidence is available in the literature.

List of allotted candidates and vacancy position after conclusion of the web counseling are placed in the web.

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Candidates have been asked to report at the respective institutions on or 4. Seats left unfilled at the end of Final phase are indicated in the vacancy position placed in web site.

The spot admissions should be conducted after completing the internal sliding first at the institution level. The Candidates who have passed all the subjects of 3 year Degree course i.

Candidates possessing the qualifying examination certificate from any university recognized by UGC shall alone be considered. While effecting the internal sliding please note that, a category seat vacated by a candidate should be first given to that category candidate and if the candidate is not available the same should be diverted to OPEN CATEGORY and finally filled as per the Annexure.

Similarly, the dropout vacancies Reported but discontinued shall be given only for that category. Likewise, the not reported cases and cancelled cases should be given only for that category.

If a particular candidates is not available, they should be converted to another categories as per the Annexure i. As per the existing G.

Candidate belonging to other state and completely studied there Other State only and whose parents belong to other state and residing there only is not eligible for Admission. Further the candidates admitted during institutional spot admissions are to be informed that their spot admissions are subject to ratification by the Convenor.

This is to be made clear to every candidate on the day of conducting the spot admissions in the college. Accordingly, the Managements are requested to comply scrupulously with the following guidelines. Managements shall note that the Special Instructions now issued are applicable only in respect of candidates who are already allotted by the Convenor, but not for the candidates seeking fresh admissions or not allotted any seat during counselling.

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For this purpose, they should enclose a written consent of the candidate and list of such re-allotments shall be submitted in the following format to the Convenor. The Convenor will not do the above process. This is not applicable to internal sliding of candidates from one branch to another branch when candidates exist in both branches and either of the branch is not closed.

Certain representations are also received from the Managements that they are unable to run the college due to poor strength of allotments and requested for Allotment of these candidates to some other college. College managements shall verify the joining details available in their college login before allowing such changes and candidates figuring in the cancelation list shall not be entertained.

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Principals are requested to comply with the following: 1. If any candidate desires to cancel the admission after but before the spot admissions, the Principal is requested to endorse on the allotment order by writing Admission is cancelled and affix signature and office stamp and keep it in the office for official use in future.

How to arrive at the vacancy position? Unfilled vacancies at the end of Finalare placed in respective college login portals of B.

Deduct the number of vacancies after making adjustments as directed in Special Guidelines [Case 1 and Case 2]. Deduct the number of vacancies filled due to re-allotment from one branch to another branch internal sliding and add the resultant vacancies.

Add dropouts joined and discontinued.

Add not reported cases. Add cancellations.

The final vacancy for spot admission shall be arrived by considering A to F above. Please comply the following scrupulously: G.

Eligibility Criteria: a. Candidates who have not taken admission so far are only eligible. Candidates shall not be allowed for spot admission without original certificates.

The vacancies are to be filled first with those qualified in A. P-ICET and possessing If the vacancies are still left, Candidates who have passed the qualifying degree or its equivalent Examination with Candidates whose qualifying examination is from other state but either of the parents resided for a period of 10 years in A.

Certificates to be Verified: Please collect all original certificates viz. Candidate should not be admitted with out original certificates being produced under any circumstances. Produce the Xerox copies of all above certificates for Verification and for ratification of spot admissions made.

Principals are requested to collect from each candidate admitted through Spot admissions the following processing fee. If no girl candidates are available, they can be filled with Boy Candidates. Uploading spot admissions in the web portal i. The list shall be signed by the Principal and shall be accompanied by the Xerox copies of certificates of the following in the order for ratification along with Newspaper copy of notification for conducting Spot Admissions.Regular surveillance, early diagnosis, treatment and follow-up in a multi-disciplinary specialized setting are also recommended.

Accordingly, the Managements are requested to comply scrupulously with the following guidelines.

For this purpose, they should enclose a written consent of the candidate and list of such re-allotments shall be submitted in the following format to the Convenor. Introduction Accurate assessment of the hypothalamic-pituitary- adrenal HPA axis is essential for the management of patients with potential or suspected pituitary or hypothalamic disease that is frequent in patients with thalassemia major TM. Schedule: Paper is needed to be solved in 2 hours and 30 minutes.

Data Sufficiency and Problem Solving. Select user type as college.

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